产品概述：Purified recombinant protein of Human artemin (ARTN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding human full-length ARTN

表达系统：E. coli

种属：Human

标签类型：N-His

分子量：18.8 kDa

通用名：ARTN

总结：This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris, pH8.0, 8M Urea.

别名：ART; ENOVIN; EVN; NBN