FITC标记的肌脂蛋白抗体
产品名称： FITC标记的肌脂蛋白抗体
英文名称： Anti-Sarcolipin/FITC
产品编号： HZ-9855R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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- 邮箱 : www.shzbio.net
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Rabbit Anti-Sarcolipin/FITC Conjugated antibody
FITC标记的肌脂蛋白抗体
| 产品编号 | bs-9855R-FITC |
| 英文名称 | Anti-Sarcolipin/FITC |
| 中文名称 | FITC标记的肌脂蛋白抗体 |
| 别 名 | SARCO_HUMAN; Sarcolipin; SLN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 信号转导 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 3.7kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Sarcolipin(1-31aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008] Subunit: Associated with calcium ATPase SERCA1. Subcellular Location: Sarcoplasmic reticulum membrane; Single-pass membrane protein. Similarity: Belongs to the sarcolipin family. Database links: Entrez Gene: 6588 Human Omim: 602203 Human SwissProt: O00631 Human Unigene: 334629 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Sarcolipin (SLN)是新近发现存在于肌浆网中的小分子膜蛋白,分子质量为3 kD,由31个氨基酸构成，与受磷蛋白(phospholamban,PLB)属于同一蛋白家族。SLN可抑制肌浆网钙泵(sarcoplasmic reticulum Ca2+ ATPase,SERCA)活性，降低其与Ca2+的亲和力，通过独立或与PLB协同作用影响SERCA活性，导致细胞内钙稳态失衡，降低心肌收缩力，从而发展为心衰 |
Sarcoplasmic reticulum Ca（2 +）-ATPase是跨膜蛋白，催化钙（2＋）从细胞质中转运到肌细胞网中的肌浆网内腔。该基因编码一个小的蛋白脂质，调节一些肌浆网CA（2 +）- ATPases。跨膜蛋白与Ca~（2+）- ATPases相互作用，减少Ca~（2+）在肌浆网中的积累，而不影响ATP水解率。[ RefSeq，JUL 2008 ]